She has many publications about pain, and her research program on pain has been continuously funded since 1986 by five institutes at the National Institutes of Health, the Patient Centered Outcomes Research Institute (PCORI), and several foundations. Currently, she is conducting a randomized clinical trial testing the effects of computerized pain tools on hospice outcomes of patients with cancer and characterizing the pain phenotype of adults with sickle cell disease and its association with their genetic and epigenetic characteristics, and several pilot studies. The long-term goal of her research is to help clinicians effectively combine pharmacologic and non-pharmacologic therapies for management of acute, chronic, and cancer pain.